STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APBA1Amyloid beta precursor protein binding family A member 1. (843 aa)    
Predicted Functional Partners:
STXBP1
Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family.
   
 0.991
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 0.988
APP
Amyloid beta precursor protein.
   
 
 0.894
STXBP2
Syntaxin binding protein 2; Belongs to the STXBP/unc-18/SEC1 family.
   
 0.798
STX1B
Syntaxin 1B; Belongs to the syntaxin family.
   
 0.783
STX1A
Syntaxin 1A; Belongs to the syntaxin family.
   
 0.781
LIN7A
Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.
    
 0.759
MPP1
Membrane palmitoylated protein 1; Belongs to the MAGUK family.
   
 0.755
RIMS2
Regulating synaptic membrane exocytosis 2.
   
 
 0.705
ZFP62
ZFP62 zinc finger protein.
      
 0.703
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.