STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCCC2Methylcrotonoyl-CoA carboxylase 2. (607 aa)    
Predicted Functional Partners:
MCCC1
Methylcrotonoyl-CoA carboxylase 1.
 
 0.999
PCCA
Propionyl-CoA carboxylase subunit alpha.
 
 0.989
BCKDHA
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.946
IVD
Isovaleryl-CoA dehydrogenase.
 
 
 0.931
PC
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
 
 0.930
HLCS
Holocarboxylase synthetase.
  
 
 0.922
NELFCD
Negative elongation factor complex member C/D.
  
 0.900
DBT
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 
 0.880
MCAT
Malonyl-CoA-acyl carrier protein transacylase.
  
 
 0.871
BCKDHB
Branched chain keto acid dehydrogenase E1 subunit beta.
  
 
 0.865
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.