STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARL1ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family. (193 aa)    
Predicted Functional Partners:
ARFIP1
ADP ribosylation factor interacting protein 1.
   
 0.904
GBF1
Golgi brefeldin A resistant guanine nucleotide exchange factor 1.
   
 0.895
CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family.
   
  
 0.871
SCOC
Short coiled-coil protein.
   
 
 0.832
ITSN2
Intersectin 2.
    
 0.821
GOLGA4
Golgin A4.
   
 0.800
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
   
 0.795
RAB6A
RAB6A, member RAS oncogene family.
   
 0.788
RAB6B
Uncharacterized protein.
   
 0.786
ARFGEF1
ADP ribosylation factor guanine nucleotide exchange factor 1.
    
 0.777
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.