STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PYCR1Pyrroline-5-carboxylate reductase 1. (445 aa)    
Predicted Functional Partners:
PYCR3
Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.
  
 
 
0.944
LOC100050480
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
   
 0.926
LOC111772327
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
   
 0.926
PRODH2
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
   
 0.926
P4HA2
Prolyl 4-hydroxylase subunit alpha 2.
     
 0.923
P4HA3
Prolyl 4-hydroxylase subunit alpha 3.
     
 0.902
PYCR2
Uncharacterized protein.
  
  
 
0.902
LAP3
Leucine aminopeptidase 3.
    
  0.900
P4HA1
Prolyl 4-hydroxylase subunit alpha 1.
     
  0.900
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.807
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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