CXCL12 protein (Equus caballus) - STRING interaction network

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protein homology

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Score

CXCL12

C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)

Predicted Functional Partners:

ACKR3

0.999

CXCR4

0.999

CXCL10

0.995

CCL5

0.990

LOC100063059

0.986

CCL25

0.986

CXCL11

0.984

CCR7

0.982

PPBP

0.978

CXCL14

0.972

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACKR3	CCL25	ENSECAP00000000611	ENSECAP00000017766	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine ligand 25.	0.698
ACKR3	CCL5	ENSECAP00000000611	ENSECAP00000022430	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family.	0.509
ACKR3	CCR7	ENSECAP00000000611	ENSECAP00000003375	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.519
ACKR3	CXCL10	ENSECAP00000000611	ENSECAP00000011110	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine.	0.620
ACKR3	CXCL11	ENSECAP00000000611	ENSECAP00000010001	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine.	0.955
ACKR3	CXCL12	ENSECAP00000000611	ENSECAP00000054268	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.999
ACKR3	CXCR4	ENSECAP00000000611	ENSECAP00000002602	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.993
ACKR3	LOC100063059	ENSECAP00000000611	ENSECAP00000011903	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	SCY domain-containing protein.	0.697
ACKR3	PPBP	ENSECAP00000000611	ENSECAP00000010413	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine.	0.411
CCL25	ACKR3	ENSECAP00000017766	ENSECAP00000000611	C-C motif chemokine ligand 25.	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.698
CCL25	CCL5	ENSECAP00000017766	ENSECAP00000022430	C-C motif chemokine ligand 25.	C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family.	0.977
CCL25	CCR7	ENSECAP00000017766	ENSECAP00000003375	C-C motif chemokine ligand 25.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.950
CCL25	CXCL10	ENSECAP00000017766	ENSECAP00000011110	C-C motif chemokine ligand 25.	C-X-C motif chemokine.	0.850
CCL25	CXCL11	ENSECAP00000017766	ENSECAP00000010001	C-C motif chemokine ligand 25.	C-X-C motif chemokine.	0.982
CCL25	CXCL12	ENSECAP00000017766	ENSECAP00000054268	C-C motif chemokine ligand 25.	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.986
CCL25	CXCL14	ENSECAP00000017766	ENSECAP00000043211	C-C motif chemokine ligand 25.	C-X-C motif chemokine ligand 14.	0.462
CCL25	CXCR4	ENSECAP00000017766	ENSECAP00000002602	C-C motif chemokine ligand 25.	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.923
CCL25	LOC100063059	ENSECAP00000017766	ENSECAP00000011903	C-C motif chemokine ligand 25.	SCY domain-containing protein.	0.745
CCL25	PPBP	ENSECAP00000017766	ENSECAP00000010413	C-C motif chemokine ligand 25.	C-X-C motif chemokine.	0.430
CCL5	ACKR3	ENSECAP00000022430	ENSECAP00000000611	C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family.	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.509