STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (456 aa)    
Predicted Functional Partners:
MAP2K4
Mitogen-activated protein kinase kinase 4.
   
 
 0.923
MAP2K7
Mitogen-activated protein kinase kinase 7.
   
 0.918
MAP2K3
Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.
   
 0.916
MAP2K6
Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.
    
 0.914
SMAD2
Mothers against decapentaplegic homolog.
   
 0.838
SMAD4
Mothers against decapentaplegic homolog.
   
 0.786
ZDHHC1
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
    
 
 0.690
PPM1B
Protein phosphatase, Mg2+/Mn2+ dependent 1B.
  
 
0.661
SMAD3
Mothers against decapentaplegic homolog.
   
 0.653
PTP4A3
TYR_PHOSPHATASE_2 domain-containing protein.
   
  
 0.652
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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