THRA protein (Equus caballus) - STRING interaction network

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Predicted Interactions

gene neighborhood

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Score

THRA

Thyroid hormone receptor alpha. (614 aa)

Predicted Functional Partners:

PIK3R1

0.949

PIK3R2

0.931

LOC100052122

0.927

MED1

0.923

NCOR1

0.918

PIK3CB

0.916

PIK3CD

0.913

PIK3CA

0.913

THRB

0.912

ACTB

0.907

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	PIK3CA	ENSECAP00000013637	ENSECAP00000013092	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.415
ACTB	THRA	ENSECAP00000013637	ENSECAP00000054814	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Thyroid hormone receptor alpha.	0.907
LOC100052122	PIK3CA	ENSECAP00000031451	ENSECAP00000013092	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.998
LOC100052122	PIK3CB	ENSECAP00000031451	ENSECAP00000021883	Uncharacterized protein.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.997
LOC100052122	PIK3CD	ENSECAP00000031451	ENSECAP00000005743	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.997
LOC100052122	PIK3R1	ENSECAP00000031451	ENSECAP00000017836	Uncharacterized protein.	Phosphoinositide-3-kinase regulatory subunit 1.	0.989
LOC100052122	PIK3R2	ENSECAP00000031451	ENSECAP00000023307	Uncharacterized protein.	Uncharacterized protein.	0.980
LOC100052122	THRA	ENSECAP00000031451	ENSECAP00000054814	Uncharacterized protein.	Thyroid hormone receptor alpha.	0.927
LOC100052122	THRB	ENSECAP00000031451	ENSECAP00000050715	Uncharacterized protein.	Thyroid hormone receptor beta.	0.927
MED1	NCOR1	ENSECAP00000007560	ENSECAP00000045299	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor corepressor 1.	0.612
MED1	THRA	ENSECAP00000007560	ENSECAP00000054814	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Thyroid hormone receptor alpha.	0.923
MED1	THRB	ENSECAP00000007560	ENSECAP00000050715	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Thyroid hormone receptor beta.	0.895
NCOR1	MED1	ENSECAP00000045299	ENSECAP00000007560	Nuclear receptor corepressor 1.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.612
NCOR1	THRA	ENSECAP00000045299	ENSECAP00000054814	Nuclear receptor corepressor 1.	Thyroid hormone receptor alpha.	0.918
NCOR1	THRB	ENSECAP00000045299	ENSECAP00000050715	Nuclear receptor corepressor 1.	Thyroid hormone receptor beta.	0.929
PIK3CA	ACTB	ENSECAP00000013092	ENSECAP00000013637	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.415
PIK3CA	LOC100052122	ENSECAP00000013092	ENSECAP00000031451	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Uncharacterized protein.	0.998
PIK3CA	PIK3CB	ENSECAP00000013092	ENSECAP00000021883	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.977
PIK3CA	PIK3CD	ENSECAP00000013092	ENSECAP00000005743	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.964
PIK3CA	PIK3R1	ENSECAP00000013092	ENSECAP00000017836	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Phosphoinositide-3-kinase regulatory subunit 1.	0.999