NRG1 protein (Equus caballus) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

NRG1

Neuregulin 1. (712 aa)

Predicted Functional Partners:

ERBB4

0.999

ERBB3

0.999

ERBB2

0.999

EGFR

0.984

NRG2

0.981

NRG4

0.959

NRG3

0.915

EGF

0.833

BACE1

0.781

MPZ

0.719

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BACE1	NRG1	ENSECAP00000010514	ENSECAP00000055225	Beta-secretase 1; Belongs to the peptidase A1 family.	Neuregulin 1.	0.781
EGF	EGFR	ENSECAP00000009190	ENSECAP00000035347	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.999
EGF	ERBB2	ENSECAP00000009190	ENSECAP00000027916	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.995
EGF	ERBB3	ENSECAP00000009190	ENSECAP00000022150	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Erb-b2 receptor tyrosine kinase 3.	0.994
EGF	ERBB4	ENSECAP00000009190	ENSECAP00000020577	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.990
EGF	NRG1	ENSECAP00000009190	ENSECAP00000055225	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Neuregulin 1.	0.833
EGF	NRG2	ENSECAP00000009190	ENSECAP00000030631	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Neuregulin 2.	0.593
EGFR	EGF	ENSECAP00000035347	ENSECAP00000009190	Receptor protein-tyrosine kinase.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.999
EGFR	ERBB2	ENSECAP00000035347	ENSECAP00000027916	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.998
EGFR	ERBB3	ENSECAP00000035347	ENSECAP00000022150	Receptor protein-tyrosine kinase.	Erb-b2 receptor tyrosine kinase 3.	0.984
EGFR	ERBB4	ENSECAP00000035347	ENSECAP00000020577	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.839
EGFR	NRG1	ENSECAP00000035347	ENSECAP00000055225	Receptor protein-tyrosine kinase.	Neuregulin 1.	0.984
EGFR	NRG2	ENSECAP00000035347	ENSECAP00000030631	Receptor protein-tyrosine kinase.	Neuregulin 2.	0.978
EGFR	NRG4	ENSECAP00000035347	ENSECAP00000023041	Receptor protein-tyrosine kinase.	Neuregulin 4.	0.495
ERBB2	EGF	ENSECAP00000027916	ENSECAP00000009190	Receptor protein-tyrosine kinase.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.995
ERBB2	EGFR	ENSECAP00000027916	ENSECAP00000035347	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.998
ERBB2	ERBB3	ENSECAP00000027916	ENSECAP00000022150	Receptor protein-tyrosine kinase.	Erb-b2 receptor tyrosine kinase 3.	0.998
ERBB2	ERBB4	ENSECAP00000027916	ENSECAP00000020577	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.992
ERBB2	MPZ	ENSECAP00000027916	ENSECAP00000042161	Receptor protein-tyrosine kinase.	Myelin protein P0; Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction. Belongs to the myelin P0 protein family.	0.408
ERBB2	NRG1	ENSECAP00000027916	ENSECAP00000055225	Receptor protein-tyrosine kinase.	Neuregulin 1.	0.999