A0A2V1DFF6 protein (Periconia macrospinosa) - STRING interaction network

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A0A2V1DFF6

P-loop containing nucleoside triphosphate hydrolase protein. (216 aa)

Predicted Functional Partners:

A0A2V1D1G9

0.812

A0A2V1E078

0.704

A0A2V1DFH7

0.687

A0A2V1DJY4

0.673

A0A2V1DPE0

0.659

A0A2V1E2T0

0.655

A0A2V1ECR6

0.655

A0A2V1DBS8

0.642

A0A2V1DNC0

0.642

A0A2V1DNT3

0.642

Your Current Organism:

Periconia macrospinosa

NCBI taxonomy Id: 97972
Other names: P. macrospinosa

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2V1D1G9	A0A2V1DBS8	P-loop containing nucleoside triphosphate hydrolase protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.642
A0A2V1D1G9	A0A2V1DFF6	P-loop containing nucleoside triphosphate hydrolase protein.	P-loop containing nucleoside triphosphate hydrolase protein.	0.812
A0A2V1D1G9	A0A2V1DFH7	P-loop containing nucleoside triphosphate hydrolase protein.	RecQ mediated genome instability protein-like protein Rmi1.	0.687
A0A2V1D1G9	A0A2V1DJY4	P-loop containing nucleoside triphosphate hydrolase protein.	DNA repair protein-like protein RAD1.	0.673
A0A2V1D1G9	A0A2V1DNC0	P-loop containing nucleoside triphosphate hydrolase protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.642
A0A2V1D1G9	A0A2V1DNT3	P-loop containing nucleoside triphosphate hydrolase protein.	Uncharacterized protein.	0.642
A0A2V1D1G9	A0A2V1DPE0	P-loop containing nucleoside triphosphate hydrolase protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.659
A0A2V1D1G9	A0A2V1E078	P-loop containing nucleoside triphosphate hydrolase protein.	P-loop containing nucleoside triphosphate hydrolase protein.	0.704
A0A2V1D1G9	A0A2V1E2T0	P-loop containing nucleoside triphosphate hydrolase protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.655
A0A2V1D1G9	A0A2V1ECR6	P-loop containing nucleoside triphosphate hydrolase protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.655
A0A2V1DBS8	A0A2V1D1G9	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	P-loop containing nucleoside triphosphate hydrolase protein.	0.642
A0A2V1DBS8	A0A2V1DFF6	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	P-loop containing nucleoside triphosphate hydrolase protein.	0.642
A0A2V1DBS8	A0A2V1DFH7	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	RecQ mediated genome instability protein-like protein Rmi1.	0.959
A0A2V1DBS8	A0A2V1DJY4	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	DNA repair protein-like protein RAD1.	0.951
A0A2V1DBS8	A0A2V1DPE0	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.974
A0A2V1DBS8	A0A2V1E078	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	P-loop containing nucleoside triphosphate hydrolase protein.	0.915
A0A2V1DBS8	A0A2V1E2T0	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.718
A0A2V1DBS8	A0A2V1ECR6	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.769
A0A2V1DFF6	A0A2V1D1G9	P-loop containing nucleoside triphosphate hydrolase protein.	P-loop containing nucleoside triphosphate hydrolase protein.	0.812
A0A2V1DFF6	A0A2V1DBS8	P-loop containing nucleoside triphosphate hydrolase protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.642