A0A2V1DMZ8 protein (Periconia macrospinosa) - STRING interaction network

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A0A2V1DMZ8

ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (485 aa)

Predicted Functional Partners:

A0A2V1EBT6

0.849

A0A2V1D0U1

0.822

A0A2V1DAD6

0.763

FEN1

0.746

A0A2V1DBS8

0.739

A0A2V1DNC0

0.739

A0A2V1E078

0.719

A0A2V1EBU5

0.711

A0A2V1DJY4

0.708

A0A2V1D0A6

0.701

Your Current Organism:

Periconia macrospinosa

NCBI taxonomy Id: 97972
Other names: P. macrospinosa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A2V1D0A6	A0A2V1DBS8	A0A2V1D0A6	A0A2V1DBS8	Uncharacterized protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.787
A0A2V1D0A6	A0A2V1DJY4	A0A2V1D0A6	A0A2V1DJY4	Uncharacterized protein.	DNA repair protein-like protein RAD1.	0.908
A0A2V1D0A6	A0A2V1DMZ8	A0A2V1D0A6	A0A2V1DMZ8	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.701
A0A2V1D0A6	A0A2V1DNC0	A0A2V1D0A6	A0A2V1DNC0	Uncharacterized protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.787
A0A2V1D0A6	A0A2V1E078	A0A2V1D0A6	A0A2V1E078	Uncharacterized protein.	P-loop containing nucleoside triphosphate hydrolase protein.	0.705
A0A2V1D0A6	FEN1	A0A2V1D0A6	A0A2V1DMB1	Uncharacterized protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.873
A0A2V1D0U1	A0A2V1DMZ8	A0A2V1D0U1	A0A2V1DMZ8	RPOL4c domain-containing protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.822
A0A2V1D0U1	A0A2V1EBT6	A0A2V1D0U1	A0A2V1EBT6	RPOL4c domain-containing protein.	DNA-directed RNA polymerase II 19 kDa polypeptide.	0.999
A0A2V1DAD6	A0A2V1DMZ8	A0A2V1DAD6	A0A2V1DMZ8	Guanylate kinase.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.763
A0A2V1DBS8	A0A2V1D0A6	A0A2V1DBS8	A0A2V1D0A6	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Uncharacterized protein.	0.787
A0A2V1DBS8	A0A2V1DJY4	A0A2V1DBS8	A0A2V1DJY4	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	DNA repair protein-like protein RAD1.	0.951
A0A2V1DBS8	A0A2V1DMZ8	A0A2V1DBS8	A0A2V1DMZ8	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.739
A0A2V1DBS8	A0A2V1E078	A0A2V1DBS8	A0A2V1E078	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	P-loop containing nucleoside triphosphate hydrolase protein.	0.915
A0A2V1DBS8	FEN1	A0A2V1DBS8	A0A2V1DMB1	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.709
A0A2V1DJY4	A0A2V1D0A6	A0A2V1DJY4	A0A2V1D0A6	DNA repair protein-like protein RAD1.	Uncharacterized protein.	0.908
A0A2V1DJY4	A0A2V1DBS8	A0A2V1DJY4	A0A2V1DBS8	DNA repair protein-like protein RAD1.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.951
A0A2V1DJY4	A0A2V1DMZ8	A0A2V1DJY4	A0A2V1DMZ8	DNA repair protein-like protein RAD1.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.708
A0A2V1DJY4	A0A2V1DNC0	A0A2V1DJY4	A0A2V1DNC0	DNA repair protein-like protein RAD1.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.951
A0A2V1DJY4	A0A2V1E078	A0A2V1DJY4	A0A2V1E078	DNA repair protein-like protein RAD1.	P-loop containing nucleoside triphosphate hydrolase protein.	0.948
A0A2V1DJY4	FEN1	A0A2V1DJY4	A0A2V1DMB1	DNA repair protein-like protein RAD1.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.892