STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OAI13140.1Ion channel protein Tsx; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)    
Predicted Functional Partners:
OAI17777.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.618
OAI13450.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.597
OAI12848.1
Pilus assembly protein PilZ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.562
OAI21081.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.557
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.550
OAI21080.1
4-vinyl reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.527
OAI18293.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.518
OAI13110.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.517
OAI13111.1
CDP-diacylglycerol--serine O-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.517
OAI16328.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.491
Your Current Organism:
Methylomonas lenta
NCBI taxonomy Id: 980561
Other names: JCM 19378, LMG 26260, LMG:26260, M. lenta, Methylomonas lenta Hoefman et al. 2014, Methylomonas sp. R-45370, Methylomonas sp. R-45377, strain R-45377
Server load: low (12%) [HD]