STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEP12423.13-octaprenyl-4hydroxybenzoate decarboxylase; Belongs to the UbiD family. (482 aa)    
Predicted Functional Partners:
ubiX
Polyprenyl P-hydroxybenzoate-like phenylacrylic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
 
 0.994
AEP11933.1
Putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family.
 
  
 0.975
menG
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
 
  
 0.784
AEP12422.1
Aminopeptidase N.
       0.773
AEP12421.1
Doubled CXXCH motif (Paired_CXXCH_1).
       0.693
mqnA
Putative periplasmic solute-binding protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
 
   
 0.686
AEP10972.1
2-polyprenylphenol hydroxylase-like flavodoxin oxidoreductase.
  
    0.530
mqnE
Radical SAM domain protein, CofH subfamily; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.
 
   
 0.428
mqnD
Putative periplasmic solute-binding protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.
  
   
 0.426
Your Current Organism:
Chloracidobacterium thermophilum
NCBI taxonomy Id: 981222
Other names: C. thermophilum B, Candidatus Chloracidobacterium thermophilum B, Chloracidobacterium thermophilum B, Chloracidobacterium thermophilum str. B, Chloracidobacterium thermophilum strain B
Server load: low (22%) [HD]