JAK1 protein (Procavia capensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

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[Homology]

Score

JAK1

Janus kinase 1. (1153 aa)

Predicted Functional Partners:

STAT1

0.999

ENSPCAP00000009640

0.998

IFNLR1

0.997

IL2RB

0.997

ENSPCAP00000007000

0.996

ENSPCAP00000012948

0.996

IL10RA

0.995

ENSPCAP00000008959

0.994

STAT2

0.989

ENSPCAP00000012906

0.989

Your Current Organism:

Procavia capensis

NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPCAP00000007000	ENSPCAP00000008959	ENSPCAP00000007000	ENSPCAP00000008959	annotation not available	annotation not available	0.999
ENSPCAP00000007000	ENSPCAP00000009640	ENSPCAP00000007000	ENSPCAP00000009640	annotation not available	annotation not available	0.936
ENSPCAP00000007000	ENSPCAP00000012906	ENSPCAP00000007000	ENSPCAP00000012906	annotation not available	annotation not available	0.535
ENSPCAP00000007000	ENSPCAP00000012948	ENSPCAP00000007000	ENSPCAP00000012948	annotation not available	annotation not available	0.957
ENSPCAP00000007000	IFNLR1	ENSPCAP00000007000	ENSPCAP00000007479	annotation not available	Interferon lambda receptor 1.	0.936
ENSPCAP00000007000	IL10RA	ENSPCAP00000007000	ENSPCAP00000000221	annotation not available	Interleukin 10 receptor subunit alpha.	0.797
ENSPCAP00000007000	JAK1	ENSPCAP00000007000	ENSPCAP00000000020	annotation not available	Janus kinase 1.	0.996
ENSPCAP00000007000	STAT1	ENSPCAP00000007000	ENSPCAP00000005546	annotation not available	Signal transducer and activator of transcription 1.	0.997
ENSPCAP00000007000	STAT2	ENSPCAP00000007000	ENSPCAP00000007405	annotation not available	Signal transducer and activator of transcription 2.	0.998
ENSPCAP00000008959	ENSPCAP00000007000	ENSPCAP00000008959	ENSPCAP00000007000	annotation not available	annotation not available	0.999
ENSPCAP00000008959	ENSPCAP00000009640	ENSPCAP00000008959	ENSPCAP00000009640	annotation not available	annotation not available	0.877
ENSPCAP00000008959	ENSPCAP00000012906	ENSPCAP00000008959	ENSPCAP00000012906	annotation not available	annotation not available	0.520
ENSPCAP00000008959	ENSPCAP00000012948	ENSPCAP00000008959	ENSPCAP00000012948	annotation not available	annotation not available	0.971
ENSPCAP00000008959	IFNLR1	ENSPCAP00000008959	ENSPCAP00000007479	annotation not available	Interferon lambda receptor 1.	0.986
ENSPCAP00000008959	IL10RA	ENSPCAP00000008959	ENSPCAP00000000221	annotation not available	Interleukin 10 receptor subunit alpha.	0.961
ENSPCAP00000008959	IL2RB	ENSPCAP00000008959	ENSPCAP00000009348	annotation not available	Interleukin 2 receptor subunit beta.	0.845
ENSPCAP00000008959	JAK1	ENSPCAP00000008959	ENSPCAP00000000020	annotation not available	Janus kinase 1.	0.994
ENSPCAP00000008959	STAT1	ENSPCAP00000008959	ENSPCAP00000005546	annotation not available	Signal transducer and activator of transcription 1.	0.991
ENSPCAP00000008959	STAT2	ENSPCAP00000008959	ENSPCAP00000007405	annotation not available	Signal transducer and activator of transcription 2.	0.998
ENSPCAP00000009640	ENSPCAP00000007000	ENSPCAP00000009640	ENSPCAP00000007000	annotation not available	annotation not available	0.936