Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACVR2AActivin A receptor type 2A. (542 aa)    
Predicted Functional Partners:
ACVR1B
Activin A receptor type 1B.
   
 0.991
INHBA
Inhibin subunit beta A.
   
 0.988
ENSPCAP00000003987
annotation not available
   
 0.977
BMP4
Bone morphogenetic protein 4.
    
 0.975
BMP2
Bone morphogenetic protein 2.
    
 0.975
MSTN
Myostatin.
   
 0.973
BMPR1A
Bone morphogenetic protein receptor type 1A.
   
 0.967
ACVR1
Activin A receptor type 1.
   
 0.964
ACVR1C
Activin A receptor type 1C.
   
 0.958
TGFBR1
Transforming growth factor beta receptor 1.
   
 0.949
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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