Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAPK3Mitogen-activated protein kinase 3. (377 aa)    
Predicted Functional Partners:
TP53
Tumor protein p53.
    
 0.985
RPS6KA1
Ribosomal protein S6 kinase A1.
    
 0.984
PTPN7
Protein tyrosine phosphatase non-receptor type 7.
    
 0.983
ENSPCAP00000005571
annotation not available
    
 0.982
RPS6KA3
Ribosomal protein S6 kinase A3.
   
 0.982
PTPRR
Protein tyrosine phosphatase receptor type R.
    
 0.982
ATF2
Activating transcription factor 2.
   
 0.981
MYC
MYC proto-oncogene, bHLH transcription factor.
    
 0.972
ENSPCAP00000014347
annotation not available
    
 0.968
HIF1A
Hypoxia inducible factor 1 subunit alpha.
    
 0.967
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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