FAM122B protein (Procavia capensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

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Co-occurrence

Co-expression

Experiments

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[Homology]

Score

FAM122B

Family with sequence similarity 122B. (260 aa)

Predicted Functional Partners:

PPP2R2C

0.910

ENSPCAP00000006868

0.872

ENSPCAP00000016037

0.860

ENSPCAP00000015875

0.734

PPP2R2A

0.734

PPP2R1B

0.726

PPP2R1A

0.726

RCAN2

0.671

RCAN3

0.671

DENND5B

0.573

Your Current Organism:

Procavia capensis

NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DENND5B	FAM122B	ENSPCAP00000000661	ENSPCAP00000001244	DENN domain containing 5B.	Family with sequence similarity 122B.	0.573
ENSPCAP00000006868	ENSPCAP00000015875	ENSPCAP00000006868	ENSPCAP00000015875	annotation not available	annotation not available	0.991
ENSPCAP00000006868	FAM122B	ENSPCAP00000006868	ENSPCAP00000001244	annotation not available	Family with sequence similarity 122B.	0.872
ENSPCAP00000006868	PPP2R1A	ENSPCAP00000006868	ENSPCAP00000007651	annotation not available	Protein phosphatase 2 scaffold subunit Aalpha.	0.989
ENSPCAP00000006868	PPP2R1B	ENSPCAP00000006868	ENSPCAP00000000285	annotation not available	Protein phosphatase 2 scaffold subunit Abeta.	0.989
ENSPCAP00000006868	PPP2R2A	ENSPCAP00000006868	ENSPCAP00000016032	annotation not available	Protein phosphatase 2 regulatory subunit Balpha.	0.991
ENSPCAP00000006868	PPP2R2C	ENSPCAP00000006868	ENSPCAP00000005744	annotation not available	Protein phosphatase 2 regulatory subunit Bgamma.	0.955
ENSPCAP00000015875	ENSPCAP00000006868	ENSPCAP00000015875	ENSPCAP00000006868	annotation not available	annotation not available	0.991
ENSPCAP00000015875	FAM122B	ENSPCAP00000015875	ENSPCAP00000001244	annotation not available	Family with sequence similarity 122B.	0.734
ENSPCAP00000015875	PPP2R1A	ENSPCAP00000015875	ENSPCAP00000007651	annotation not available	Protein phosphatase 2 scaffold subunit Aalpha.	0.968
ENSPCAP00000015875	PPP2R1B	ENSPCAP00000015875	ENSPCAP00000000285	annotation not available	Protein phosphatase 2 scaffold subunit Abeta.	0.968
ENSPCAP00000015875	PPP2R2A	ENSPCAP00000015875	ENSPCAP00000016032	annotation not available	Protein phosphatase 2 regulatory subunit Balpha.	0.841
ENSPCAP00000015875	PPP2R2C	ENSPCAP00000015875	ENSPCAP00000005744	annotation not available	Protein phosphatase 2 regulatory subunit Bgamma.	0.966
ENSPCAP00000016037	FAM122B	ENSPCAP00000016037	ENSPCAP00000001244	annotation not available	Family with sequence similarity 122B.	0.860
ENSPCAP00000016037	RCAN2	ENSPCAP00000016037	ENSPCAP00000013545	annotation not available	Regulator of calcineurin 2.	0.883
ENSPCAP00000016037	RCAN3	ENSPCAP00000016037	ENSPCAP00000015218	annotation not available	RCAN family member 3.	0.883
FAM122B	DENND5B	ENSPCAP00000001244	ENSPCAP00000000661	Family with sequence similarity 122B.	DENN domain containing 5B.	0.573
FAM122B	ENSPCAP00000006868	ENSPCAP00000001244	ENSPCAP00000006868	Family with sequence similarity 122B.	annotation not available	0.872
FAM122B	ENSPCAP00000015875	ENSPCAP00000001244	ENSPCAP00000015875	Family with sequence similarity 122B.	annotation not available	0.734
FAM122B	ENSPCAP00000016037	ENSPCAP00000001244	ENSPCAP00000016037	Family with sequence similarity 122B.	annotation not available	0.860