STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHHSonic hedgehog signaling molecule. (456 aa)    
Predicted Functional Partners:
CDON
Cell adhesion associated, oncogene regulated.
    
 0.990
PTCH1
Patched 1.
    
 0.984
PTCH2
Patched 2.
   
 0.976
BOC
BOC cell adhesion associated, oncogene regulated.
    
 0.974
HHIP
Hedgehog interacting protein.
    
 0.972
DISP1
Dispatched RND transporter family member 1.
    
 0.956
GPC3
Glypican 3.
    
 0.929
LRP2
LDL receptor related protein 2.
     
 0.919
DHH
Desert hedgehog signaling molecule.
  
  
0.898
IHH
Indian hedgehog signaling molecule.
  
  
 
0.883
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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