STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHHSonic hedgehog signaling molecule. (456 aa)    
Predicted Functional Partners:
PTCH1
Patched 1.
   
 0.992
DISP1
Dispatched RND transporter family member 1.
    
 0.983
HHIP
Hedgehog interacting protein.
    
 0.983
PTCH2
Patched 2.
   
 0.982
CDON
Cell adhesion associated, oncogene regulated.
    
 0.980
BOC
BOC cell adhesion associated, oncogene regulated.
    
 0.977
SMO
Smoothened, frizzled class receptor.
    
 0.933
GPC3
Glypican 3.
    
 0.931
GAS1
Growth arrest specific 1.
    
 0.927
VPS53
VPS53 subunit of GARP complex.
    
 0.894
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.