STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAPGEF5Rap guanine nucleotide exchange factor 5. (728 aa)    
Predicted Functional Partners:
RAP1B
RAP1B, member of RAS oncogene family.
    
 0.964
ENSPCAP00000007837
annotation not available
    
 0.958
ENSPCAP00000011395
annotation not available
    
 0.948
KRAS
KRAS proto-oncogene, GTPase.
    
 0.869
ERAS
ES cell expressed Ras.
    
 0.867
NRAS
NRAS proto-oncogene, GTPase.
    
 0.867
RIT2
Ras like without CAAX 2.
    
 0.847
CSDE1
Cold shock domain containing E1.
    
 0.826
RAP2B
RAP2B, member of RAS oncogene family.
    
 0.801
DIRAS1
DIRAS family GTPase 1.
    
 0.772
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.