ASIC4 protein (Procavia capensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

ASIC4

Acid sensing ion channel subunit family member 4. (660 aa)

Predicted Functional Partners:

ASIC3

0.904

ASIC1

0.844

ENSPCAP00000014883

0.844

ASIC2

0.844

STOML1

0.705

PNKD

0.679

SCN3B

0.659

ENSPCAP00000011322

0.659

NALCN

0.654

STOML3

0.650

Your Current Organism:

Procavia capensis

NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASIC1	ASIC3	ENSPCAP00000011070	ENSPCAP00000006804	Acid sensing ion channel subunit 1.	Acid sensing ion channel subunit 3.	0.853
ASIC1	ASIC4	ENSPCAP00000011070	ENSPCAP00000001459	Acid sensing ion channel subunit 1.	Acid sensing ion channel subunit family member 4.	0.844
ASIC1	ENSPCAP00000011322	ENSPCAP00000011070	ENSPCAP00000011322	Acid sensing ion channel subunit 1.	annotation not available	0.435
ASIC1	NALCN	ENSPCAP00000011070	ENSPCAP00000014179	Acid sensing ion channel subunit 1.	Sodium leak channel, non-selective.	0.480
ASIC1	SCN3B	ENSPCAP00000011070	ENSPCAP00000004201	Acid sensing ion channel subunit 1.	Sodium voltage-gated channel beta subunit 3.	0.511
ASIC1	STOML1	ENSPCAP00000011070	ENSPCAP00000009066	Acid sensing ion channel subunit 1.	Stomatin like 1.	0.698
ASIC1	STOML3	ENSPCAP00000011070	ENSPCAP00000004100	Acid sensing ion channel subunit 1.	Stomatin like 3.	0.654
ASIC2	ASIC3	ENSPCAP00000015557	ENSPCAP00000006804	Acid sensing ion channel subunit 2.	Acid sensing ion channel subunit 3.	0.853
ASIC2	ASIC4	ENSPCAP00000015557	ENSPCAP00000001459	Acid sensing ion channel subunit 2.	Acid sensing ion channel subunit family member 4.	0.844
ASIC2	ENSPCAP00000011322	ENSPCAP00000015557	ENSPCAP00000011322	Acid sensing ion channel subunit 2.	annotation not available	0.435
ASIC2	NALCN	ENSPCAP00000015557	ENSPCAP00000014179	Acid sensing ion channel subunit 2.	Sodium leak channel, non-selective.	0.480
ASIC2	SCN3B	ENSPCAP00000015557	ENSPCAP00000004201	Acid sensing ion channel subunit 2.	Sodium voltage-gated channel beta subunit 3.	0.511
ASIC2	STOML1	ENSPCAP00000015557	ENSPCAP00000009066	Acid sensing ion channel subunit 2.	Stomatin like 1.	0.698
ASIC2	STOML3	ENSPCAP00000015557	ENSPCAP00000004100	Acid sensing ion channel subunit 2.	Stomatin like 3.	0.654
ASIC3	ASIC1	ENSPCAP00000006804	ENSPCAP00000011070	Acid sensing ion channel subunit 3.	Acid sensing ion channel subunit 1.	0.853
ASIC3	ASIC2	ENSPCAP00000006804	ENSPCAP00000015557	Acid sensing ion channel subunit 3.	Acid sensing ion channel subunit 2.	0.853
ASIC3	ASIC4	ENSPCAP00000006804	ENSPCAP00000001459	Acid sensing ion channel subunit 3.	Acid sensing ion channel subunit family member 4.	0.904
ASIC3	ENSPCAP00000011322	ENSPCAP00000006804	ENSPCAP00000011322	Acid sensing ion channel subunit 3.	annotation not available	0.435
ASIC3	ENSPCAP00000014883	ENSPCAP00000006804	ENSPCAP00000014883	Acid sensing ion channel subunit 3.	annotation not available	0.853
ASIC3	NALCN	ENSPCAP00000006804	ENSPCAP00000014179	Acid sensing ion channel subunit 3.	Sodium leak channel, non-selective.	0.480