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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRKACAProtein kinase cAMP-activated catalytic subunit alpha. (350 aa)    
Predicted Functional Partners:
PRKAR1A
Protein kinase cAMP-dependent type I regulatory subunit alpha.
 
 
 0.996
PRKAR1B
Protein kinase cAMP-dependent type I regulatory subunit beta.
 
 
 0.995
PKIA
cAMP-dependent protein kinase inhibitor alpha.
   
 0.990
RYR2
Ryanodine receptor 2.
    
 0.974
PRKAR2A
Protein kinase cAMP-dependent type II regulatory subunit alpha.
   
 0.970
PRKAR2B
Protein kinase cAMP-dependent type II regulatory subunit beta.
   
 0.969
SMO
Smoothened, frizzled class receptor.
    
 0.949
ENSPCAP00000004419
annotation not available
   
 0.943
CREB1
cAMP responsive element binding protein 1.
    
 0.942
PDE4B
Phosphodiesterase 4B.
   
 0.942
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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