STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1299 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
   
 0.996
EGFR
Epidermal growth factor receptor.
    
 0.984
SHC1
SHC adaptor protein 1.
    
 0.970
SHC3
SHC adaptor protein 3.
    
 0.970
ENSPCAP00000012906
annotation not available
    
 0.963
PTPN11
Protein tyrosine phosphatase non-receptor type 11.
    
 0.963
NRAS
NRAS proto-oncogene, GTPase.
   
 0.956
KRAS
KRAS proto-oncogene, GTPase.
   
 0.952
FGFR3
Fibroblast growth factor receptor 3.
    
 0.947
ENSPCAP00000011395
annotation not available
    
 0.942
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.