STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CASP8Caspase 8. (533 aa)    
Predicted Functional Partners:
CFLAR
CASP8 and FADD like apoptosis regulator.
   
 0.994
ENSPCAP00000007574
annotation not available
   
 0.994
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.994
CASP3
Caspase 3.
   
 0.993
ENSPCAP00000002707
annotation not available
   
 0.991
TRADD
TNFRSF1A associated via death domain.
   
 0.991
CASP6
Caspase 6.
   
 0.981
CASP7
Caspase 7.
   
 0.980
ENSPCAP00000012735
annotation not available
    
 0.978
PYCARD
PYD and CARD domain containing.
   
 0.977
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.