STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP8Caspase 8. (533 aa)    
Predicted Functional Partners:
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.990
ENSPCAP00000002707
annotation not available
   
 0.989
CFLAR
CASP8 and FADD like apoptosis regulator.
   
0.989
TRADD
TNFRSF1A associated via death domain.
    
 0.977
CASP3
Caspase 3.
  
0.974
CASP6
Caspase 6.
   
0.959
PYCARD
PYD and CARD domain containing.
   
 0.954
APAF1
Apoptotic peptidase activating factor 1.
    
 0.948
CASP7
Caspase 7.
   
0.944
BCL10
BCL10 immune signaling adaptor.
   
 0.940
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.