KLKB1 protein (Procavia capensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

KLKB1

Kallikrein B1. (634 aa)

Predicted Functional Partners:

SERPING1

0.786

ENSPCAP00000000255

0.757

ENSPCAP00000003113

0.726

PRCC

0.726

F12

0.723

HGFAC

0.713

ENSPCAP00000011283

0.712

ENSPCAP00000008074

0.697

ENSPCAP00000009761

0.695

ACE2

0.673

Your Current Organism:

Procavia capensis

NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACE2	ENSPCAP00000000255	ENSPCAP00000012014	ENSPCAP00000000255	Angiotensin I converting enzyme 2.	annotation not available	0.568
ACE2	ENSPCAP00000009761	ENSPCAP00000012014	ENSPCAP00000009761	Angiotensin I converting enzyme 2.	annotation not available	0.543
ACE2	ENSPCAP00000011283	ENSPCAP00000012014	ENSPCAP00000011283	Angiotensin I converting enzyme 2.	annotation not available	0.574
ACE2	F12	ENSPCAP00000012014	ENSPCAP00000007612	Angiotensin I converting enzyme 2.	Coagulation factor XII.	0.419
ACE2	HGFAC	ENSPCAP00000012014	ENSPCAP00000004797	Angiotensin I converting enzyme 2.	HGF activator.	0.419
ACE2	KLKB1	ENSPCAP00000012014	ENSPCAP00000001571	Angiotensin I converting enzyme 2.	Kallikrein B1.	0.673
ACE2	SERPING1	ENSPCAP00000012014	ENSPCAP00000001043	Angiotensin I converting enzyme 2.	Serpin family G member 1.	0.414
ENSPCAP00000000255	ACE2	ENSPCAP00000000255	ENSPCAP00000012014	annotation not available	Angiotensin I converting enzyme 2.	0.568
ENSPCAP00000000255	ENSPCAP00000003113	ENSPCAP00000000255	ENSPCAP00000003113	annotation not available	annotation not available	0.607
ENSPCAP00000000255	ENSPCAP00000008074	ENSPCAP00000000255	ENSPCAP00000008074	annotation not available	annotation not available	0.881
ENSPCAP00000000255	ENSPCAP00000009761	ENSPCAP00000000255	ENSPCAP00000009761	annotation not available	annotation not available	0.960
ENSPCAP00000000255	F12	ENSPCAP00000000255	ENSPCAP00000007612	annotation not available	Coagulation factor XII.	0.609
ENSPCAP00000000255	HGFAC	ENSPCAP00000000255	ENSPCAP00000004797	annotation not available	HGF activator.	0.609
ENSPCAP00000000255	KLKB1	ENSPCAP00000000255	ENSPCAP00000001571	annotation not available	Kallikrein B1.	0.757
ENSPCAP00000000255	SERPING1	ENSPCAP00000000255	ENSPCAP00000001043	annotation not available	Serpin family G member 1.	0.671
ENSPCAP00000003113	ENSPCAP00000000255	ENSPCAP00000003113	ENSPCAP00000000255	annotation not available	annotation not available	0.607
ENSPCAP00000003113	ENSPCAP00000008074	ENSPCAP00000003113	ENSPCAP00000008074	annotation not available	annotation not available	0.648
ENSPCAP00000003113	ENSPCAP00000009761	ENSPCAP00000003113	ENSPCAP00000009761	annotation not available	annotation not available	0.810
ENSPCAP00000003113	F12	ENSPCAP00000003113	ENSPCAP00000007612	annotation not available	Coagulation factor XII.	0.554
ENSPCAP00000003113	HGFAC	ENSPCAP00000003113	ENSPCAP00000004797	annotation not available	HGF activator.	0.554