HR protein (Procavia capensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

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Co-occurrence

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[Homology]

Score

HR

HR lysine demethylase and nuclear receptor corepressor. (1173 aa)

Predicted Functional Partners:

PPARG

0.858

ENSPCAP00000004559

0.850

SMARCE1

0.829

SMARCD2

0.829

PRKACA

0.700

PRKACB

0.700

ARID1A

0.697

ARID1B

0.697

SMARCC1

0.696

SMARCC2

0.696

Your Current Organism:

Procavia capensis

NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARID1A	ARID1B	ENSPCAP00000011565	ENSPCAP00000012094	AT-rich interaction domain 1A.	AT-rich interaction domain 1B.	0.841
ARID1A	ENSPCAP00000004559	ENSPCAP00000011565	ENSPCAP00000004559	AT-rich interaction domain 1A.	annotation not available	0.993
ARID1A	HR	ENSPCAP00000011565	ENSPCAP00000001607	AT-rich interaction domain 1A.	HR lysine demethylase and nuclear receptor corepressor.	0.697
ARID1A	PPARG	ENSPCAP00000011565	ENSPCAP00000000943	AT-rich interaction domain 1A.	Peroxisome proliferator activated receptor gamma.	0.872
ARID1A	SMARCC1	ENSPCAP00000011565	ENSPCAP00000005196	AT-rich interaction domain 1A.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1.	0.970
ARID1A	SMARCC2	ENSPCAP00000011565	ENSPCAP00000005727	AT-rich interaction domain 1A.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2.	0.970
ARID1A	SMARCD2	ENSPCAP00000011565	ENSPCAP00000002552	AT-rich interaction domain 1A.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2.	0.987
ARID1A	SMARCE1	ENSPCAP00000011565	ENSPCAP00000001160	AT-rich interaction domain 1A.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1.	0.991
ARID1B	ARID1A	ENSPCAP00000012094	ENSPCAP00000011565	AT-rich interaction domain 1B.	AT-rich interaction domain 1A.	0.841
ARID1B	ENSPCAP00000004559	ENSPCAP00000012094	ENSPCAP00000004559	AT-rich interaction domain 1B.	annotation not available	0.993
ARID1B	HR	ENSPCAP00000012094	ENSPCAP00000001607	AT-rich interaction domain 1B.	HR lysine demethylase and nuclear receptor corepressor.	0.697
ARID1B	PPARG	ENSPCAP00000012094	ENSPCAP00000000943	AT-rich interaction domain 1B.	Peroxisome proliferator activated receptor gamma.	0.872
ARID1B	SMARCC1	ENSPCAP00000012094	ENSPCAP00000005196	AT-rich interaction domain 1B.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1.	0.970
ARID1B	SMARCC2	ENSPCAP00000012094	ENSPCAP00000005727	AT-rich interaction domain 1B.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2.	0.970
ARID1B	SMARCD2	ENSPCAP00000012094	ENSPCAP00000002552	AT-rich interaction domain 1B.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2.	0.987
ARID1B	SMARCE1	ENSPCAP00000012094	ENSPCAP00000001160	AT-rich interaction domain 1B.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1.	0.991
ENSPCAP00000004559	ARID1A	ENSPCAP00000004559	ENSPCAP00000011565	annotation not available	AT-rich interaction domain 1A.	0.993
ENSPCAP00000004559	ARID1B	ENSPCAP00000004559	ENSPCAP00000012094	annotation not available	AT-rich interaction domain 1B.	0.993
ENSPCAP00000004559	HR	ENSPCAP00000004559	ENSPCAP00000001607	annotation not available	HR lysine demethylase and nuclear receptor corepressor.	0.850
ENSPCAP00000004559	PPARG	ENSPCAP00000004559	ENSPCAP00000000943	annotation not available	Peroxisome proliferator activated receptor gamma.	0.878