STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TDP1tyrosyl-DNA phosphodiesterase 1. (612 aa)    
Predicted Functional Partners:
LIG3
DNA ligase 3.
   
 
 0.990
TOP1
DNA topoisomerase I.
    
 
 0.985
XRCC1
X-ray repair cross complementing 1.
   
 
 0.981
POLB
DNA polymerase beta.
    
 
 0.978
APLF
Aprataxin and PNKP like factor.
    
 
 0.978
ERCC4
ERCC excision repair 4, endonuclease catalytic subunit.
   
 
 0.955
PNKP
Polynucleotide kinase 3'-phosphatase.
    
 
 0.933
APTX
Aprataxin.
    
 
 0.924
APEX1
Apurinic/apyrimidinic endodeoxyribonuclease 1.
   
 
 0.907
ENSPCAP00000010722
annotation not available
   
 
 0.896
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.