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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TDP1tyrosyl-DNA phosphodiesterase 1. (612 aa)    
Predicted Functional Partners:
TOP1
DNA topoisomerase I.
    
 
 0.957
ERCC4
ERCC excision repair 4, endonuclease catalytic subunit.
   
 
 0.850
XRCC6
X-ray repair cross complementing 6.
     
 0.848
LIG3
DNA ligase 3.
   
 
 0.846
XRCC5
X-ray repair cross complementing 5.
    
 0.842
MUS81
MUS81 structure-specific endonuclease subunit.
   
 
 0.839
XRCC1
X-ray repair cross complementing 1.
   
 
 0.838
ENSPCAP00000010722
annotation not available
   
 
 0.836
APEX1
Apurinic/apyrimidinic endodeoxyribonuclease 1.
   
 
 0.822
LIG1
DNA ligase 1.
   
 
 0.818
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.