Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DENND5ADENN domain containing 5A. (1288 aa)    
Predicted Functional Partners:
DENND4C
DENN domain containing 4C.
    
 0.992
DENND5B
DENN domain containing 5B.
   
   0.967
VPS26A
VPS26, retromer complex component A.
     
 0.963
SNX1
Sorting nexin 1.
     
 0.960
ENSPCAP00000011121
annotation not available
     
 0.938
SNX2
Sorting nexin 2.
     
 0.936
ANKFY1
Ankyrin repeat and FYVE domain containing 1.
    
  0.932
VPS35
VPS35 retromer complex component.
   
 
  0.932
ENSPCAP00000007336
annotation not available
     
 0.931
ENSPCAP00000001472
annotation not available
     
  0.930
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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