Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BDH23-hydroxybutyrate dehydrogenase 2. (243 aa)    
Predicted Functional Partners:
BDH1
3-hydroxybutyrate dehydrogenase 1.
     
 0.921
OXCT1
3-oxoacid CoA-transferase 1.
  
 0.893
AACS
acetoacetyl-CoA synthetase.
    
 0.876
HMGCL
3-hydroxy-3-methylglutaryl-CoA lyase.
  
 
 0.777
HMGCLL1
3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1.
  
 
 0.777
ACADL
acyl-CoA dehydrogenase long chain.
  
 0.774
ACAA1
acetyl-CoA acyltransferase 1.
  
 0.751
ECI2
enoyl-CoA delta isomerase 2.
  
 0.733
EHHADH
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase.
  
 0.721
OXSM
3-oxoacyl-ACP synthase, mitochondrial.
  
 0.713
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
Server load: low (22%) [HD]