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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH3PXD2BSH3 and PX domains 2B. (814 aa)    
Predicted Functional Partners:
ADAM15
ADAM metallopeptidase domain 15.
    
 0.768
NCF2
Neutrophil cytosolic factor 2.
    
 0.748
PAK2
P21 (RAC1) activated kinase 2.
    
 0.735
PAK6
P21 (RAC1) activated kinase 6.
    
 0.735
PAK5
P21 (RAC1) activated kinase 5.
    
 0.735
PAK1
P21 (RAC1) activated kinase 1.
    
 0.735
PAK4
P21 (RAC1) activated kinase 4.
    
 0.735
PAK3
P21 (RAC1) activated kinase 3.
    
 0.735
ENSPCAP00000013796
annotation not available
    
 0.717
SORBS2
Sorbin and SH3 domain containing 2.
    
 0.701
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.