Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SH3PXD2BSH3 and PX domains 2B. (814 aa)    
Predicted Functional Partners:
PHACTR2
Phosphatase and actin regulator 2.
      
 0.848
ADAM15
ADAM metallopeptidase domain 15.
    
 0.795
MMP14
Matrix metallopeptidase 14.
   
 
 0.722
NCK2
NCK adaptor protein 2.
    
 
 0.705
WASL
WASP like actin nucleation promoting factor.
   
 0.643
NCF2
Neutrophil cytosolic factor 2.
   
 0.643
ENSPCAP00000010648
annotation not available
    
 0.615
ENSPCAP00000013796
annotation not available
   
 0.613
PAK2
P21 (RAC1) activated kinase 2.
    
 0.607
PAK6
P21 (RAC1) activated kinase 6.
    
 0.607
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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