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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUL4BCullin 4B. (912 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
   
 0.992
DCAF1
DDB1 and CUL4 associated factor 1.
   
 0.987
RBX1
Ring-box 1.
    
 0.975
DTL
Denticleless E3 ubiquitin protein ligase homolog.
    
 0.965
ENSPCAP00000007188
annotation not available
    
 0.955
ENSPCAP00000013557
annotation not available
    
 0.942
NEDD8
NEDD8 ubiquitin like modifier.
    
 0.928
COPS4
COP9 signalosome subunit 4.
    
 0.926
COPS2
COP9 signalosome subunit 2.
  
 0.924
DDB2
Damage specific DNA binding protein 2.
    
 0.923
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.