Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CUL4BCullin 4B. (912 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
   
 0.994
CRBN
Cereblon.
    
 0.993
DCAF1
DDB1 and CUL4 associated factor 1.
   
 0.993
RBX1
Ring-box 1.
    
 0.993
DTL
Denticleless E3 ubiquitin protein ligase homolog.
    
 0.993
DCAF11
DDB1 and CUL4 associated factor 11.
    
 0.992
DDB2
Damage specific DNA binding protein 2.
    
 0.992
ENSPCAP00000007188
annotation not available
    
 0.991
DDA1
DET1 and DDB1 associated 1.
    
 0.989
COP1
COP1 E3 ubiquitin ligase.
    
 0.988
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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