Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IQGAP2IQ motif containing GTPase activating protein 2. (1574 aa)    
Predicted Functional Partners:
ENSPCAP00000010648
annotation not available
   
 0.989
CTNNB1
Catenin beta 1.
   
 0.970
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.878
MYL6B
Myosin light chain 6B.
    
  0.875
MYL6
Myosin light chain 6.
    
 0.875
CD44
CD44 molecule (Indian blood group).
   
 0.874
RAC1
Rac family small GTPase 1.
   
 0.858
ENSPCAP00000002179
annotation not available
   
 0.858
RAC3
Rac family small GTPase 3.
   
 0.858
MAPK3
Mitogen-activated protein kinase 3.
    
 0.850
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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