Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
L2HGDHL-2-hydroxyglutarate dehydrogenase. (462 aa)    
Predicted Functional Partners:
ALDH4A1
Aldehyde dehydrogenase 4 family member A1.
  
 
 0.893
ENSPCAP00000008097
annotation not available
    
 0.874
ENSPCAP00000009274
annotation not available
    
 0.874
ALDH5A1
Aldehyde dehydrogenase 5 family member A1.
  
 
 0.868
GAD2
Glutamate decarboxylase 2.
     
 0.867
GLS
Glutaminase.
     
 0.867
GAD1
Glutamate decarboxylase 1.
     
 0.867
GLS2
Glutaminase 2.
     
 0.866
FH
Fumarate hydratase.
    
 0.853
ENSPCAP00000010998
annotation not available
     
 0.849
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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