STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (655 aa)    
Predicted Functional Partners:
MAP2K5
Mitogen-activated protein kinase kinase 5.
   
0.994
CCM2
CCM2 scaffold protein.
    
 0.967
PAK1
P21 (RAC1) activated kinase 1.
  
 
0.943
PAK2
P21 (RAC1) activated kinase 2.
  
 
0.942
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
  
0.935
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
 0.933
MAP3K2
Mitogen-activated protein kinase kinase kinase 2.
  
 
 
0.929
MAP2K6
Mitogen-activated protein kinase kinase 6.
  
0.925
MAP2K3
Mitogen-activated protein kinase kinase 3.
  
0.924
SQSTM1
Sequestosome 1.
    
 0.921
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.