Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZNRF3Zinc and ring finger 3. (829 aa)    
Predicted Functional Partners:
RSPO2
R-spondin 2.
    
 0.915
RSPO1
R-spondin 1.
    
 0.907
FZD4
Frizzled class receptor 4.
    
 0.887
FZD1
Frizzled class receptor 1.
    
 0.882
FZD3
Frizzled class receptor 3.
    
 0.881
FZD6
Frizzled class receptor 6.
    
 0.876
RSPO3
R-spondin 3.
    
 0.873
ENSPCAP00000014262
annotation not available
    
 0.793
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
    
 0.722
SFRP1
Secreted frizzled related protein 1.
    
 0.651
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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