Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OPA1OPA1 mitochondrial dynamin like GTPase. (978 aa)    
Predicted Functional Partners:
MFN1
Mitofusin 1.
   
 0.990
OMA1
OMA1 zinc metallopeptidase.
   
 0.981
MFN2
Mitofusin 2.
   
 0.979
PINK1
PTEN induced kinase 1.
    
 0.965
PRKN
Parkin RBR E3 ubiquitin protein ligase.
    
 0.886
ENSPCAP00000000690
annotation not available
   
 0.870
IMMT
Inner membrane mitochondrial protein.
   
 0.858
ITSN2
Intersectin 2.
    
 
 0.826
LRRK2
Leucine rich repeat kinase 2.
    
 0.769
ENSPCAP00000009255
annotation not available
   
 
 0.751
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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