Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PBX1PBX homeobox 1. (428 aa)    
Predicted Functional Partners:
HOXB6
Homeobox B6.
    
 0.884
HOXC4
Homeobox C4.
    
 0.873
PKNOX1
PBX/knotted 1 homeobox 1.
    
 0.869
SIRT1
Sirtuin 1.
     
  0.863
PRKACB
Protein kinase cAMP-activated catalytic subunit beta.
     
  0.863
HOXD1
Homeobox D1.
    
 0.860
HOXB7
Homeobox B7.
    
 0.845
MEIS2
Meis homeobox 2.
   
 0.845
MEIS1
Meis homeobox 1.
   
 0.845
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha.
     
  0.841
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
Server load: low (20%) [HD]