Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLXNB1Plexin B1. (2130 aa)    
Predicted Functional Partners:
RND1
Rho family GTPase 1.
    
 0.988
SEMA4D
Semaphorin 4D.
    
 0.988
MET
MET proto-oncogene, receptor tyrosine kinase.
    
 0.968
ARHGEF11
Rho guanine nucleotide exchange factor 11.
    
 0.964
RND3
Rho family GTPase 3.
    
 0.961
ARHGEF12
Rho guanine nucleotide exchange factor 12.
    
 0.935
SEMA4C
Semaphorin 4C.
    
 0.926
SEMA4G
Semaphorin 4G.
    
 0.926
SEMA4F
Ssemaphorin 4F.
    
 0.926
PLXND1
Plexin D1.
   
 0.921
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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