Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PNKPPolynucleotide kinase 3'-phosphatase. (521 aa)    
Predicted Functional Partners:
POLB
DNA polymerase beta.
    
 0.998
XRCC1
X-ray repair cross complementing 1.
   
 0.995
LIG3
DNA ligase 3.
   
 0.994
ENSPCAP00000002787
annotation not available
     
 0.958
ENSPCAP00000005146
annotation not available
  
 
 0.958
FCSK
Fucose kinase.
  
 
 0.938
TDP1
tyrosyl-DNA phosphodiesterase 1.
    
 
 0.933
POLL
DNA polymerase lambda.
    
 0.918
CCDC43
Coiled-coil domain containing 43.
    
   0.916
APTX
Aprataxin.
    
 0.909
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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