CELSR3 protein (Procavia capensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CELSR3

Cadherin EGF LAG seven-pass G-type receptor 3. (4126 aa)

Predicted Functional Partners:

VANGL1

0.722

FZD3

0.668

VANGL2

0.615

EFNB3

0.550

ENSPCAP00000014503

0.495

ENSPCAP00000004692

0.490

ENSPCAP00000007546

0.490

FZD6

0.483

PRICKLE3

0.464

OBSL1

0.463

Your Current Organism:

Procavia capensis

NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CELSR3	EFNB3	ENSPCAP00000002887	ENSPCAP00000012020	Cadherin EGF LAG seven-pass G-type receptor 3.	Ephrin B3.	0.550
CELSR3	ENSPCAP00000004692	ENSPCAP00000002887	ENSPCAP00000004692	Cadherin EGF LAG seven-pass G-type receptor 3.	annotation not available	0.490
CELSR3	ENSPCAP00000007546	ENSPCAP00000002887	ENSPCAP00000007546	Cadherin EGF LAG seven-pass G-type receptor 3.	annotation not available	0.490
CELSR3	ENSPCAP00000014503	ENSPCAP00000002887	ENSPCAP00000014503	Cadherin EGF LAG seven-pass G-type receptor 3.	annotation not available	0.495
CELSR3	FZD3	ENSPCAP00000002887	ENSPCAP00000001733	Cadherin EGF LAG seven-pass G-type receptor 3.	Frizzled class receptor 3.	0.668
CELSR3	FZD6	ENSPCAP00000002887	ENSPCAP00000007023	Cadherin EGF LAG seven-pass G-type receptor 3.	Frizzled class receptor 6.	0.483
CELSR3	OBSL1	ENSPCAP00000002887	ENSPCAP00000001611	Cadherin EGF LAG seven-pass G-type receptor 3.	Obscurin like cytoskeletal adaptor 1.	0.463
CELSR3	PRICKLE3	ENSPCAP00000002887	ENSPCAP00000014830	Cadherin EGF LAG seven-pass G-type receptor 3.	Prickle planar cell polarity protein 3.	0.464
CELSR3	VANGL1	ENSPCAP00000002887	ENSPCAP00000000778	Cadherin EGF LAG seven-pass G-type receptor 3.	VANGL planar cell polarity protein 1.	0.722
CELSR3	VANGL2	ENSPCAP00000002887	ENSPCAP00000008224	Cadherin EGF LAG seven-pass G-type receptor 3.	VANGL planar cell polarity protein 2.	0.615
EFNB3	CELSR3	ENSPCAP00000012020	ENSPCAP00000002887	Ephrin B3.	Cadherin EGF LAG seven-pass G-type receptor 3.	0.550
ENSPCAP00000004692	CELSR3	ENSPCAP00000004692	ENSPCAP00000002887	annotation not available	Cadherin EGF LAG seven-pass G-type receptor 3.	0.490
ENSPCAP00000004692	ENSPCAP00000007546	ENSPCAP00000004692	ENSPCAP00000007546	annotation not available	annotation not available	0.975
ENSPCAP00000004692	VANGL1	ENSPCAP00000004692	ENSPCAP00000000778	annotation not available	VANGL planar cell polarity protein 1.	0.412
ENSPCAP00000004692	VANGL2	ENSPCAP00000004692	ENSPCAP00000008224	annotation not available	VANGL planar cell polarity protein 2.	0.412
ENSPCAP00000007546	CELSR3	ENSPCAP00000007546	ENSPCAP00000002887	annotation not available	Cadherin EGF LAG seven-pass G-type receptor 3.	0.490
ENSPCAP00000007546	ENSPCAP00000004692	ENSPCAP00000007546	ENSPCAP00000004692	annotation not available	annotation not available	0.975
ENSPCAP00000007546	VANGL1	ENSPCAP00000007546	ENSPCAP00000000778	annotation not available	VANGL planar cell polarity protein 1.	0.412
ENSPCAP00000007546	VANGL2	ENSPCAP00000007546	ENSPCAP00000008224	annotation not available	VANGL planar cell polarity protein 2.	0.412
ENSPCAP00000014503	CELSR3	ENSPCAP00000014503	ENSPCAP00000002887	annotation not available	Cadherin EGF LAG seven-pass G-type receptor 3.	0.495