Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAGED2MAGE family member D2. (593 aa)    
Predicted Functional Partners:
NSMCE4A
NSE4 homolog A, SMC5-SMC6 complex component.
   
 0.997
NSMCE1
NSE1 homolog, SMC5-SMC6 complex component.
   
 0.997
SMC5
Structural maintenance of chromosomes 5.
   
 0.990
NSMCE2
NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase.
    
 0.988
SMC6
Structural maintenance of chromosomes 6.
   
 0.988
NGFR
Nerve growth factor receptor.
    
 0.960
TP53
Tumor protein p53.
    
 0.951
EID1
EP300 interacting inhibitor of differentiation 1.
   
 
 0.927
E2F1
E2F transcription factor 1.
    
 
 0.870
RIC8B
RIC8 guanine nucleotide exchange factor B.
    
   0.844
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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