STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)    
Predicted Functional Partners:
RAPGEF1
Rap guanine nucleotide exchange factor 1.
    
 0.995
CBL
Cbl proto-oncogene.
    
 0.994
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.980
EGFR
Epidermal growth factor receptor.
    
 0.979
ABL1
ABL proto-oncogene 1, non-receptor tyrosine kinase.
    
0.970
CBLB
Cbl proto-oncogene B.
    
 0.969
DOCK1
Dedicator of cytokinesis 1.
    
 0.968
ABL2
ABL proto-oncogene 2, non-receptor tyrosine kinase.
    
0.967
ENSPCAP00000015427
annotation not available
    
 0.954
ELMO1
Engulfment and cell motility 1.
    
 0.945
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.