LRIG3 protein (Procavia capensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

LRIG3

Leucine rich repeats and immunoglobulin like domains 3. (1123 aa)

Predicted Functional Partners:

ENSPCAP00000006548

0.957

LRIG1

0.955

ERBB2

0.903

DCC

0.793

NEO1

0.793

ROS1

0.736

MST1R

0.732

MET

0.732

ENSPCAP00000006514

0.714

RGMB

0.714

Your Current Organism:

Procavia capensis

NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCC	ENSPCAP00000006514	ENSPCAP00000000193	ENSPCAP00000006514	DCC netrin 1 receptor.	annotation not available	0.951
DCC	LRIG1	ENSPCAP00000000193	ENSPCAP00000005970	DCC netrin 1 receptor.	Leucine rich repeats and immunoglobulin like domains 1.	0.665
DCC	LRIG3	ENSPCAP00000000193	ENSPCAP00000003274	DCC netrin 1 receptor.	Leucine rich repeats and immunoglobulin like domains 3.	0.793
DCC	RGMB	ENSPCAP00000000193	ENSPCAP00000014752	DCC netrin 1 receptor.	Repulsive guidance molecule BMP co-receptor b.	0.925
ENSPCAP00000006514	DCC	ENSPCAP00000006514	ENSPCAP00000000193	annotation not available	DCC netrin 1 receptor.	0.951
ENSPCAP00000006514	LRIG1	ENSPCAP00000006514	ENSPCAP00000005970	annotation not available	Leucine rich repeats and immunoglobulin like domains 1.	0.666
ENSPCAP00000006514	LRIG3	ENSPCAP00000006514	ENSPCAP00000003274	annotation not available	Leucine rich repeats and immunoglobulin like domains 3.	0.714
ENSPCAP00000006514	NEO1	ENSPCAP00000006514	ENSPCAP00000004764	annotation not available	Neogenin 1.	0.989
ENSPCAP00000006548	LRIG1	ENSPCAP00000006548	ENSPCAP00000005970	annotation not available	Leucine rich repeats and immunoglobulin like domains 1.	0.888
ENSPCAP00000006548	LRIG3	ENSPCAP00000006548	ENSPCAP00000003274	annotation not available	Leucine rich repeats and immunoglobulin like domains 3.	0.957
ERBB2	LRIG1	ENSPCAP00000006065	ENSPCAP00000005970	Erb-b2 receptor tyrosine kinase 2.	Leucine rich repeats and immunoglobulin like domains 1.	0.967
ERBB2	LRIG3	ENSPCAP00000006065	ENSPCAP00000003274	Erb-b2 receptor tyrosine kinase 2.	Leucine rich repeats and immunoglobulin like domains 3.	0.903
ERBB2	MET	ENSPCAP00000006065	ENSPCAP00000009228	Erb-b2 receptor tyrosine kinase 2.	MET proto-oncogene, receptor tyrosine kinase.	0.991
ERBB2	MST1R	ENSPCAP00000006065	ENSPCAP00000005117	Erb-b2 receptor tyrosine kinase 2.	Macrophage stimulating 1 receptor.	0.959
ERBB2	ROS1	ENSPCAP00000006065	ENSPCAP00000000812	Erb-b2 receptor tyrosine kinase 2.	ROS proto-oncogene 1, receptor tyrosine kinase.	0.726
LRIG1	DCC	ENSPCAP00000005970	ENSPCAP00000000193	Leucine rich repeats and immunoglobulin like domains 1.	DCC netrin 1 receptor.	0.665
LRIG1	ENSPCAP00000006514	ENSPCAP00000005970	ENSPCAP00000006514	Leucine rich repeats and immunoglobulin like domains 1.	annotation not available	0.666
LRIG1	ENSPCAP00000006548	ENSPCAP00000005970	ENSPCAP00000006548	Leucine rich repeats and immunoglobulin like domains 1.	annotation not available	0.888
LRIG1	ERBB2	ENSPCAP00000005970	ENSPCAP00000006065	Leucine rich repeats and immunoglobulin like domains 1.	Erb-b2 receptor tyrosine kinase 2.	0.967
LRIG1	LRIG3	ENSPCAP00000005970	ENSPCAP00000003274	Leucine rich repeats and immunoglobulin like domains 1.	Leucine rich repeats and immunoglobulin like domains 3.	0.955