DENND3 protein (Procavia capensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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Textmining

[Homology]

Score

DENND3

DENN domain containing 3. (1147 aa)

Predicted Functional Partners:

RAB12

0.923

UEVLD

0.913

DENND5B

0.911

ULK1

0.911

DENND5A

0.887

DENND2B

0.808

ENSPCAP00000000320

0.720

ENSPCAP00000003038

0.713

ENSPCAP00000010105

0.709

RAB10

0.669

Your Current Organism:

Procavia capensis

NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax

Export your current network:

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DENND2B	DENND3	ENSPCAP00000011171	ENSPCAP00000003333	DENN domain containing 2B.	DENN domain containing 3.	0.808
DENND2B	DENND5A	ENSPCAP00000011171	ENSPCAP00000001636	DENN domain containing 2B.	DENN domain containing 5A.	0.814
DENND2B	DENND5B	ENSPCAP00000011171	ENSPCAP00000000661	DENN domain containing 2B.	DENN domain containing 5B.	0.814
DENND2B	ENSPCAP00000003038	ENSPCAP00000011171	ENSPCAP00000003038	DENN domain containing 2B.	annotation not available	0.765
DENND2B	RAB10	ENSPCAP00000011171	ENSPCAP00000012537	DENN domain containing 2B.	RAB10, member RAS oncogene family.	0.646
DENND3	DENND2B	ENSPCAP00000003333	ENSPCAP00000011171	DENN domain containing 3.	DENN domain containing 2B.	0.808
DENND3	DENND5A	ENSPCAP00000003333	ENSPCAP00000001636	DENN domain containing 3.	DENN domain containing 5A.	0.887
DENND3	DENND5B	ENSPCAP00000003333	ENSPCAP00000000661	DENN domain containing 3.	DENN domain containing 5B.	0.911
DENND3	ENSPCAP00000000320	ENSPCAP00000003333	ENSPCAP00000000320	DENN domain containing 3.	annotation not available	0.720
DENND3	ENSPCAP00000003038	ENSPCAP00000003333	ENSPCAP00000003038	DENN domain containing 3.	annotation not available	0.713
DENND3	ENSPCAP00000010105	ENSPCAP00000003333	ENSPCAP00000010105	DENN domain containing 3.	annotation not available	0.709
DENND3	RAB10	ENSPCAP00000003333	ENSPCAP00000012537	DENN domain containing 3.	RAB10, member RAS oncogene family.	0.669
DENND3	RAB12	ENSPCAP00000003333	ENSPCAP00000014001	DENN domain containing 3.	RAB12, member RAS oncogene family.	0.923
DENND3	UEVLD	ENSPCAP00000003333	ENSPCAP00000009647	DENN domain containing 3.	UEV and lactate/malate dehyrogenase domains.	0.913
DENND3	ULK1	ENSPCAP00000003333	ENSPCAP00000004571	DENN domain containing 3.	Unc-51 like autophagy activating kinase 1.	0.911
DENND5A	DENND2B	ENSPCAP00000001636	ENSPCAP00000011171	DENN domain containing 5A.	DENN domain containing 2B.	0.814
DENND5A	DENND3	ENSPCAP00000001636	ENSPCAP00000003333	DENN domain containing 5A.	DENN domain containing 3.	0.887
DENND5A	DENND5B	ENSPCAP00000001636	ENSPCAP00000000661	DENN domain containing 5A.	DENN domain containing 5B.	0.967
DENND5A	ENSPCAP00000000320	ENSPCAP00000001636	ENSPCAP00000000320	DENN domain containing 5A.	annotation not available	0.832
DENND5A	ENSPCAP00000003038	ENSPCAP00000001636	ENSPCAP00000003038	DENN domain containing 5A.	annotation not available	0.717