Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DEDDDeath effector domain containing. (214 aa)    
Predicted Functional Partners:
REXO4
REX4 homolog, 3'-5' exonuclease.
      
 0.887
ISG20L2
Interferon stimulated exonuclease gene 20 like 2.
      
 0.883
CFLAR
CASP8 and FADD like apoptosis regulator.
    
 
 0.738
CASP8
Caspase 8.
    
 
 0.719
CASP10
Caspase 10.
    
 
 0.719
ERI1
Exoribonuclease 1.
      
 0.624
STRN4
Striatin 4.
      
 0.586
XRN1
5'-3' exoribonuclease 1.
      
 0.570
SPRY1
Sprouty RTK signaling antagonist 1.
      
 0.568
TOMM40L
Translocase of outer mitochondrial membrane 40 like.
      
 0.567
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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