close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK1P21 (RAC1) activated kinase 1. (554 aa)    
Predicted Functional Partners:
ENSPCAP00000010648
annotation not available
   
 0.989
ITSN2
Intersectin 2.
    
 0.977
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.968
NCK1
NCK adaptor protein 1.
    
 0.968
ENSPCAP00000009220
annotation not available
    
 0.965
NCK2
NCK adaptor protein 2.
    
 0.964
MAP3K3
Mitogen-activated protein kinase kinase kinase 3.
  
 
0.943
MAP3K2
Mitogen-activated protein kinase kinase kinase 2.
    
0.937
RAC1
Rac family small GTPase 1.
    
 0.929
ENSPCAP00000002179
annotation not available
    
 0.929
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.