HIPK4 protein (Procavia capensis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Cooccurrence

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Experiments

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[Homology]

Score

HIPK4

Homeodomain interacting protein kinase 4. (599 aa)

Predicted Functional Partners:

TP53

0.956

RASSF5

0.912

HIPK3

0.894

DCAF7

0.769

SUMO1

0.683

UBE2I

0.682

PIN1

0.669

EP300

0.658

CREBBP

0.646

MECP2

0.638

Your Current Organism:

Procavia capensis

NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CREBBP	EP300	ENSPCAP00000013530	ENSPCAP00000011493	CREB binding protein.	E1A binding protein p300.	0.996
CREBBP	HIPK3	ENSPCAP00000013530	ENSPCAP00000008845	CREB binding protein.	Homeodomain interacting protein kinase 3.	0.646
CREBBP	HIPK4	ENSPCAP00000013530	ENSPCAP00000003516	CREB binding protein.	Homeodomain interacting protein kinase 4.	0.646
CREBBP	MECP2	ENSPCAP00000013530	ENSPCAP00000010978	CREB binding protein.	methyl-CpG binding protein 2.	0.563
CREBBP	SUMO1	ENSPCAP00000013530	ENSPCAP00000006393	CREB binding protein.	Small ubiquitin like modifier 1.	0.979
CREBBP	TP53	ENSPCAP00000013530	ENSPCAP00000011892	CREB binding protein.	Tumor protein p53.	0.998
CREBBP	UBE2I	ENSPCAP00000013530	ENSPCAP00000007578	CREB binding protein.	Ubiquitin conjugating enzyme E2 I.	0.822
DCAF7	HIPK3	ENSPCAP00000008635	ENSPCAP00000008845	DDB1 and CUL4 associated factor 7.	Homeodomain interacting protein kinase 3.	0.769
DCAF7	HIPK4	ENSPCAP00000008635	ENSPCAP00000003516	DDB1 and CUL4 associated factor 7.	Homeodomain interacting protein kinase 4.	0.769
EP300	CREBBP	ENSPCAP00000011493	ENSPCAP00000013530	E1A binding protein p300.	CREB binding protein.	0.996
EP300	HIPK3	ENSPCAP00000011493	ENSPCAP00000008845	E1A binding protein p300.	Homeodomain interacting protein kinase 3.	0.649
EP300	HIPK4	ENSPCAP00000011493	ENSPCAP00000003516	E1A binding protein p300.	Homeodomain interacting protein kinase 4.	0.658
EP300	MECP2	ENSPCAP00000011493	ENSPCAP00000010978	E1A binding protein p300.	methyl-CpG binding protein 2.	0.538
EP300	SUMO1	ENSPCAP00000011493	ENSPCAP00000006393	E1A binding protein p300.	Small ubiquitin like modifier 1.	0.900
EP300	TP53	ENSPCAP00000011493	ENSPCAP00000011892	E1A binding protein p300.	Tumor protein p53.	0.998
EP300	UBE2I	ENSPCAP00000011493	ENSPCAP00000007578	E1A binding protein p300.	Ubiquitin conjugating enzyme E2 I.	0.735
HIPK3	CREBBP	ENSPCAP00000008845	ENSPCAP00000013530	Homeodomain interacting protein kinase 3.	CREB binding protein.	0.646
HIPK3	DCAF7	ENSPCAP00000008845	ENSPCAP00000008635	Homeodomain interacting protein kinase 3.	DDB1 and CUL4 associated factor 7.	0.769
HIPK3	EP300	ENSPCAP00000008845	ENSPCAP00000011493	Homeodomain interacting protein kinase 3.	E1A binding protein p300.	0.649
HIPK3	HIPK4	ENSPCAP00000008845	ENSPCAP00000003516	Homeodomain interacting protein kinase 3.	Homeodomain interacting protein kinase 4.	0.894