Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NTRK3Neurotrophic receptor tyrosine kinase 3. (839 aa)    
Predicted Functional Partners:
NGF
Nerve growth factor.
    
 0.996
BDNF
Brain derived neurotrophic factor.
   
 0.985
NGFR
Nerve growth factor receptor.
   
 0.981
FRS2
Fibroblast growth factor receptor substrate 2.
    
 0.975
SHC1
SHC adaptor protein 1.
   
 0.972
SHC3
SHC adaptor protein 3.
   
 0.972
ERBB2
Erb-b2 receptor tyrosine kinase 2.
   
 0.971
PLCG1
Phospholipase C gamma 1.
    
 0.971
PLCG2
Phospholipase C gamma 2.
    
 0.968
GRB2
Growth factor receptor bound protein 2.
    
 0.963
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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