Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
E2F8E2F transcription factor 8. (850 aa)    
Predicted Functional Partners:
E2F7
E2F transcription factor 7.
   
 0.981
KIF11
Kinesin family member 11.
   
  
 0.950
ENSPCAP00000011713
annotation not available
   
  
 0.934
TTK
TTK protein kinase.
   
  
 0.916
ENSPCAP00000002988
annotation not available
   
  
 0.913
KIF20A
Kinesin family member 20A.
   
  
 0.898
TOP2A
DNA topoisomerase II alpha.
   
  
 0.875
DLGAP5
DLG associated protein 5.
   
  
 0.875
CCNA2
Cyclin A2.
   
 
 0.863
ASPM
Abnormal spindle microtubule assembly.
   
  
 0.840
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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