Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EPGNEpithelial mitogen. (133 aa)    
Predicted Functional Partners:
EGFR
Epidermal growth factor receptor.
    
 0.987
ERBB3
Erb-b2 receptor tyrosine kinase 3.
    
 0.838
ERBB4
Erb-b2 receptor tyrosine kinase 4.
    
 0.838
EREG
Epiregulin.
     
 0.821
BTC
Betacellulin.
     
 0.789
HBEGF
Heparin binding EGF like growth factor.
     
 0.788
AREG
Amphiregulin.
     
 0.769
EGF
Epidermal growth factor.
    
 0.758
ERBB2
Erb-b2 receptor tyrosine kinase 2.
    
 0.751
ENSPCAP00000000859
annotation not available
     
 0.657
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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