Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
E2F3E2F transcription factor 3. (420 aa)    
Predicted Functional Partners:
RB1
RB transcriptional corepressor 1.
   
 0.995
RBL1
RB transcriptional corepressor like 1.
   
 0.990
TFDP2
Transcription factor Dp-2.
   
 0.980
E2F1
E2F transcription factor 1.
    
 0.974
RBL2
RB transcriptional corepressor like 2.
   
 0.969
E2F5
E2F transcription factor 5.
    
 0.966
E2F4
E2F transcription factor 4.
    
 0.959
CCNA2
Cyclin A2.
   
 0.946
ENSPCAP00000007115
annotation not available
   
 0.945
CDK2
Cyclin dependent kinase 2.
    
 0.930
Your Current Organism:
Procavia capensis
NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax
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