SMAD6 protein (Procavia capensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

SMAD6

SMAD family member 6. (496 aa)

Predicted Functional Partners:

ENSPCAP00000009916

0.997

SMAD1

0.996

SMAD4

0.993

SMURF2

0.986

SMAD7

0.980

TGFBR1

0.979

TGFBR2

0.971

SMAD5

0.965

SMAD9

0.963

RNF111

0.963

Your Current Organism:

Procavia capensis

NCBI taxonomy Id: 9813
Other names: Cape hyrax, Cape rock hyrax, P. capensis, large-toothed rock hyrax, rock dassie, rock hyrax

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPCAP00000009916	RNF111	ENSPCAP00000009916	ENSPCAP00000015265	annotation not available	Ring finger protein 111.	0.468
ENSPCAP00000009916	SMAD1	ENSPCAP00000009916	ENSPCAP00000008520	annotation not available	SMAD family member 1.	0.980
ENSPCAP00000009916	SMAD4	ENSPCAP00000009916	ENSPCAP00000008572	annotation not available	SMAD family member 4.	0.932
ENSPCAP00000009916	SMAD5	ENSPCAP00000009916	ENSPCAP00000006347	annotation not available	SMAD family member 5.	0.988
ENSPCAP00000009916	SMAD6	ENSPCAP00000009916	ENSPCAP00000003989	annotation not available	SMAD family member 6.	0.997
ENSPCAP00000009916	SMAD7	ENSPCAP00000009916	ENSPCAP00000014126	annotation not available	SMAD family member 7.	0.997
ENSPCAP00000009916	SMAD9	ENSPCAP00000009916	ENSPCAP00000002458	annotation not available	SMAD family member 9.	0.893
ENSPCAP00000009916	SMURF2	ENSPCAP00000009916	ENSPCAP00000006891	annotation not available	SMAD specific E3 ubiquitin protein ligase 2.	0.994
ENSPCAP00000009916	TGFBR1	ENSPCAP00000009916	ENSPCAP00000013638	annotation not available	Transforming growth factor beta receptor 1.	0.990
ENSPCAP00000009916	TGFBR2	ENSPCAP00000009916	ENSPCAP00000009312	annotation not available	Transforming growth factor beta receptor 2.	0.969
RNF111	ENSPCAP00000009916	ENSPCAP00000015265	ENSPCAP00000009916	Ring finger protein 111.	annotation not available	0.468
RNF111	SMAD1	ENSPCAP00000015265	ENSPCAP00000008520	Ring finger protein 111.	SMAD family member 1.	0.462
RNF111	SMAD4	ENSPCAP00000015265	ENSPCAP00000008572	Ring finger protein 111.	SMAD family member 4.	0.451
RNF111	SMAD5	ENSPCAP00000015265	ENSPCAP00000006347	Ring finger protein 111.	SMAD family member 5.	0.468
RNF111	SMAD6	ENSPCAP00000015265	ENSPCAP00000003989	Ring finger protein 111.	SMAD family member 6.	0.963
RNF111	SMAD7	ENSPCAP00000015265	ENSPCAP00000014126	Ring finger protein 111.	SMAD family member 7.	0.998
RNF111	SMAD9	ENSPCAP00000015265	ENSPCAP00000002458	Ring finger protein 111.	SMAD family member 9.	0.462
RNF111	SMURF2	ENSPCAP00000015265	ENSPCAP00000006891	Ring finger protein 111.	SMAD specific E3 ubiquitin protein ligase 2.	0.615
SMAD1	ENSPCAP00000009916	ENSPCAP00000008520	ENSPCAP00000009916	SMAD family member 1.	annotation not available	0.980
SMAD1	RNF111	ENSPCAP00000008520	ENSPCAP00000015265	SMAD family member 1.	Ring finger protein 111.	0.462